Joe Cascio

Our Stories

Every day, children’s hospitals help make moments possible. From providing access to the comprehensive care that children need to grow up to supporting children, teens, and their families with specialized treatment for some of the most complex illnesses. Discover more about the moments made possible by children’s hospital through patient stories from around the country.

Video Stories

Bolton’s Bravery

With specialized, comprehensive care in hospitals tailored to the unique needs of pediatric patients, children’s hospitals help children and teens like Bolton defy the odds.

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Isaac’s Impact

Children’s hospitals provide advanced care for the most complex conditions in environments specially designed for pediatric patients, allowing children like Isaac to thrive.

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Cami’s Courage

The specialized multidisciplinary teams at children’s hospitals ensure that children and teens – like Cami – can beat multiple complex conditions like cancer and heart failure.

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Joseph’s Journey

The advanced, specialized care that children’s hospitals provide make moments – like Joseph beating pediatric brain cancer – possible.

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Daniella’s Drive

With care delivered by specially trained pediatric clinicians, in environments designed just for children, children’s hospitals help children and teens – like Daniella – navigate complex medical conditions.

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Featured Story

One-time gene therapy transforms Sriansh’s future

When Sriansh was just three months old, his family grew concerned as he slept most of the day, arched his back, and could not control his eye movement. His parents brought him to Cincinnati Children’s, where he was diagnosed with AADC deficiency, a rare genetic disorder that disrupts dopamine and serotonin production in the brain. Sriansh’s family was told he might never walk, talk, or lift his head. But thanks to an experimental gene therapy clinical trial, his story took a groundbreaking turn. At just 16 months old, Sriansh became the youngest child in the world to receive one-time gene therapy treatment, delivered directly into the brain through a minimally invasive surgical technique. His care team inserted an engineered virus carrying the missing gene, allowing his brain to begin producing the essential chemicals it lacked. Today, Sriansh is walking, running, and thriving because of this innovative clinical trial. This pioneering work helped lead to the first-ever FDA-approved gene therapy administered directly to the brain, offering hope for patients with rare genetic diseases once thought untreatable. 

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Showing 119 stories

Daniella’s Drive

With care delivered by specially trained pediatric clinicians, in environments designed just for children, children’s hospitals help children and teens – like Daniella – navigate complex medical conditions.

Watch video

Joseph’s Journey

The advanced, specialized care that children’s hospitals provide make moments – like Joseph beating pediatric brain cancer – possible.

Watch video

Cami’s Courage

The specialized multidisciplinary teams at children’s hospitals ensure that children and teens – like Cami – can beat multiple complex conditions like cancer and heart failure.

Watch video

Isaac’s Impact

Children’s hospitals provide advanced care for the most complex conditions in environments specially designed for pediatric patients, allowing children like Isaac to thrive.

Watch video

Bolton’s Bravery

With specialized, comprehensive care in hospitals tailored to the unique needs of pediatric patients, children’s hospitals help children and teens like Bolton defy the odds.

Watch video